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Hormone Testing at Clinical Labs

Hormone Testing at Clinical Labs

Written by A/Prof Mirette Saad.


  • IGF-1, also referred to as somatomedin-C (Sm-C), is a hormone similar in molecular structure to insulin that is mainly produced by the liver in blood. IGF-1 mediates most of the effects of Growth Hormone (GH). It plays an important role in childhood growth and continues to have anabolic effects in adults
  • IGF-1 is produced throughout life. The highest rates of IGF-1 production occur during the pubertal growth spurt. The lowest levels occur in infancy and old age.
  • Levels of IGF-1 can vary in the circulation depending on variation in the levels of GH, insulin levels, genetic make-up, the time of day, age, sex, exercise status, stress levels, nutrition level and body mass index (BMI), disease state, ethnicity, estrogen status and xenobiotic intake.

  • IGF-1: is a clinical severity marker. It correlates with GH levels in the blood so it can be a useful marker in the diagnosis of clinical conditions such as acromegaly and GH deficiency.
  • IGF-1 can also be useful in assessing patients’ nutritional status, dwarfism, and in monitoring patients on treatment for the above conditions or patients on treatment with recombinant IGF-1.

  • IGF-1 test is a Medicare rebateable
  • Can be performed on serum or heparinised plasma samples
  • IGF1 test is performed on Siemens Immulite® XPI. Validated Age specific Reference Ranges apply.
  • Results are available to clinicians within 2-3 business days.


As part of the wide range of reproductive pathology services, Australian Clinical Labs has been offering the Anti-Müllerian Hormone (AMH) test using a fully automated Roche Cobas Elecsys® assay which shows excellent analytical performance over other methods including precision, accuracy and functional sensitivity. AMH is an established biomarker produced by antral and pre-antral follicles for assessing ovarian reserve which is considered an important tool in assessing potential fertility.


Australian Clinical Labs has introduced the new precise, reliable and robust AMH Plus Immunoassay from Roche Cobas Elecsys®. AMH PLUS enables clinicians to use results when dosing in women undergoing an assisted reproductive technology programme with the human recombinant follicle stimulating hormone (human rFSH), REKOVELLE® (follitropin delta). AMH Age-Specific Reference Ranges (10th-90th percentile) are reported as provided by Roche.


The test is performed on a gel serum tube and clinicians will receive full report of AMH with age specific reference ranges within 2-4 business days. This service is not rebateable by Medicare, and therefore will attract an out of pocket fee.


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