Progress in understanding melanomas
There has been significant progress in our understanding of melanomas, both from a pathological and clinical point of view. Several studies have increased our understanding of prognostic factors, including microscopic features of biopsies and sentinel lymph node biopsy. Advances in genetic changes have led to new therapies for melanoma. This article highlights some of these advances and explains their relevance to the way melanomas are reported.
Biopsy and histological analysis remain the standard for the diagnosis of melanoma, although this analysis has been refined.
From a histological point of view the main prognostic factors are:
1. Breslow thickness.
2. Mitotic rate.