Path Focus June 2026 - Needle Pain in Children Article

Needle Pain
in Children

Why it matters and what we can do

By Professor Jane Munro
Published June 2026

Professor Jane Munro is a paediatric rheumatologist at the Royal Children’s Hospital, Melbourne, and Director of the Victorian Children’s Clinic

The problem we've been ignoring

For most adults, a blood test is a minor inconvenience. For a child, it can be one of the most distressing experiences of their healthcare journey. Needle pain, including venepuncture, cannulation and capillary sampling, is the most common source of iatrogenic pain in children and is largely preventable.

Yet despite decades of evidence, needle pain in paediatric patients remains undertreated. Children frequently undergo procedures with no analgesic preparation, no distraction support and no recognition that their fear and pain are a clinical problem worth solving. The consequences extend beyond the moment. Poorly managed procedural pain in childhood is a well-documented driver of healthcare avoidance, needle phobia, and anxiety in adolescence and adult life.

This is a shared problem, and pathology services are uniquely placed to be part of the solution.

Why children are different

Pain is not simply a sensory experience. In children, the emotional and contextual components of pain, including anticipatory anxiety, loss of control, unfamiliar environments and parental distress, are amplified. Young children lack the cognitive tools to rationalise what is happening to them. Even older children and adolescents may display significant distress disproportionate to what adults expect.

Physiologically, children are not small adults. Their pain thresholds, metabolic responses to topical anaesthesia, and capacity to use cognitive coping strategies all vary with developmental stage. Effective pain management must be age-appropriate, not one-size-fits-all.

Fear and pain also interact in a self-reinforcing cycle. A child who has had a traumatic blood collection experience arrives at their next appointment already in a state of heightened distress - making procedural success harder and pain perception worse. Breaking this cycle early is far more effective than managing an entrenched needle phobia later.

What the evidence tells us

The good news is that we know how to manage needle pain effectively. A strong and growing evidence base, including systematic reviews, the international gold standard in this space, identifies a cluster of interventions that, used in combination, dramatically reduce pain and distress in children undergoing needle procedures (see Table 1).

These fall into three categories:

1. Topical anaesthesia

Topical local anaesthetic creams (such as EMLA or AnGEL) applied 30–60 minutes before a procedure significantly reduce pain at the needle site. They are safe, effective and underused. Incorporation into standard pre-procedure preparation, including providing families with a prescription or take-home cream for elective blood tests, is a straightforward systems change with immediate impact.

2. Positioning and physical comfort

Supine restraint, the traditional approach of lying a child flat and holding them still, is associated with greater distress, poorer outcomes and lasting psychological harm. Current best practice favours upright positioning (seated on a parent's lap for young children, sitting independently for older children) and avoidance of forceful restraint. This simple change requires no equipment and can be implemented immediately.

3. Psychological strategies

Distraction is the most evidence-supported non-pharmacological intervention for procedural pain in children.

Age-appropriate distraction (bubbles, visual toys, pinwheels or light-up toys for toddlers; videos, music, virtual reality or guided imagery for older children) actively engages the brain's attentional systems and competes with pain processing.

Coaching parents to lead distraction, rather than offering reassurance ("it'll be okay, it won't hurt"), is a nuanced but important distinction. Reassurance-focused parental behaviour is associated with increased child distress.

Sucrose solution (for infants under 12 months) and breastfeeding during procedures are also well-supported and easily implemented.

Table 1. Clinical Tips: Reducing Needle Pain and Distress in Children

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TipNotes
Apply topical anaesthetic cream before the appointmentEMLA or AnGel applied 45-60 min prior. Prescribe or advise families to source in advance for elective tests.
Position upright, not supineSeat young children on a parent's lap; older children sit independently. Avoid lying the child flat, as it increases distress and is no longer best practice.
Avoid forceful restraintRestraint worsens distress and long-term healthcare avoidance. If a child is too distressed, defer and reschedule with better preparation.
Use active distraction: age-matchedBubbles, pinwheels, or light-up toys for under-5s.
Videos or devices, music or counting games for older children. Start before the procedure begins.
Consider Buzzy® vibration + cold deviceBuzzy® uses vibration and cold to block pain signals at the site of the needle (gate control). FDA-cleared and backed by 75+ clinical studies. Available in Australia at buzzy4shots.com.au. Can complement topical cream or be used alone when cream has not been applied.
Coach parents to distract, not reassure"Watch this!" works better than "It'll be okay."
Reassurance-focused parenting is paradoxically associated with greater child distress.
Sucrose for infants under 12 monthsOral sucrose 1-2 minutes before the procedure reduces pain response. Breastfeeding during the procedure is also effective.
Bundle blood tests where possibleWork with referring clinicians to minimise the number of separate collections for children with chronic conditions.
Create a child-friendly environmentMinimise clinical cues in waiting and collection areas.
Allow a parent to remain present throughout.
Reduce waiting time where possible.
Ask before you actExplain what will happen in age-appropriate language.
Offer small choices (which arm? count to three first?) as this is building the perception of control, not total control.
Allow a moment of readiness.
Flag children with needle phobia on referralA note on the request form allows collection staff to prepare and allocate appropriate time.
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None of these require significant investment. All are supported by evidence demonstrating their effectiveness.

The role of pathology services

Pathology collection centres occupy a critical position in this story. They are often the point of care for elective blood tests, a setting where preparation time exists, where the environment can be designed to support children and where staff training can be systematically implemented.

Internationally, the ChildKind International certification program recognises healthcare facilities that demonstrate institutional commitment to paediatric pain management. Principles from this program, including staff training, standardised protocols, child-friendly environments, and pain assessment, offer a useful framework for pathology services seeking to improve practice.

What referring clinicians can do

When ordering blood tests for children, consider:

  • Bundling tests where clinically appropriate to minimise the number of collections.
  • Prescribing or recommending topical anaesthetic for elective procedures, particularly for younger children or those with known needle anxiety.
  • Flagging children with significant needle phobia on referral, so collection staff can prepare appropriately.
  • Discussing the collection experience with families before the appointment - what to bring, how to position their child and how to use distraction.

For children with chronic conditions requiring frequent blood tests - including those with juvenile idiopathic arthritis, inflammatory bowel disease, renal disease or oncological conditions - a proactive pain management plan is part of good clinical care.

A word on consent and restraint

Forceful restraint of a child for a non-emergency procedure is ethically problematic and, in most cases, clinically unnecessary when proper preparation has occurred.

Where a child is extremely distressed, deferral and rescheduling with enhanced preparation, or referral to a service with specialised paediatric care and/or procedural analgesia and sedation, is almost always preferable to proceeding under duress.

Conclusion

Needle pain is not a trivial side effect of paediatric healthcare; it is a clinical problem with documented short- and long-term consequences. The evidence base for prevention is strong, the interventions are accessible, and the opportunity for pathology services and referring clinicians to lead meaningful change is real.

Children deserve to have their pain taken seriously. Making needle procedures safer, less frightening, and less painful is not just good patient experience, it is good medicine.

At Victorian Children’s Clinic in Malvern, we have developed a pathology collection service, co-designed with Australian Clinical Labs, with a focus on paediatric pain management to deliver high-quality, child-focused procedural care.


Useful clinical resources


Paediatric Collection Services at Clinical Labs

Visit our Locations finder and filter by Paediatric Collection to locate collection centres with experienced paediatric collectors.


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References

  1. Friedrichsdorf SJ, Eull D, Weidner C, Postier A. A hospital-wide initiative to eliminate or reduce needle pain in children using lean methodology. Pain Reports 2018;3(Suppl 1):e671. doi:10.1097/PR9.0000000000000671
  2. Friedrichsdorf SJ, Goubert L. Pediatric pain treatment and prevention for hospitalized children. Pain Reports 2020;5(1):e804. doi:10.1097/ PR9.0000000000000804
  3. Postier AC, Eull D, Schulz C, et al. Pain experience in a US children’s hospital: a point prevalence survey undertaken after the implementation of a system-wide protocol to eliminate or decrease pain caused by needles. Hospital Pediatrics 2018;8(9):515–523. doi:10.1542/ hpeds.2018-0039
  4. Birnie KA, Noel M, Chambers CT, Uman LS, Parker JA. Psychological interventions for needle-related procedural pain and distress in children and adolescents. Cochrane Database of Systematic Reviews 2018;10:CD005179.
  5. Cho M-K, Choi M-Y. Effect of distraction intervention for needle-related pain and distress in children: a systematic review and meta-analysis. International Journal of Environmental Research and Public Health 2021;18(17):9159. doi:10.3390/ijerph18179159
  6. Carlotta G, et al. Non-pharmacological interventions to reduce procedural needle pain in children (6–12 years): a systematic review. Pain Management Nursing 2024. doi:10.1016/j.pmn.2024.07.003
  7. ChildKind International. Standards for paediatric pain management. childkindinternational.org