Helicobacter pylori
C14 Urea Breath Test
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Purpose of this test
This test is used for detecting the presence of bacteria called Helicobacter pylori, which can cause stomach inflammation. It may also be used to check that the bacteria have been eradicated after treatment. The capsule used in this test results in exposure to a very small amount of radiation, similar to what we receive from the general environment in a day. If you are pregnant, could be pregnant, are breastfeeding, or if the test is for a child under 12 years old, an alternative test (H. pylori stool antigen) is recommended. Please discuss this with your doctor. Patients may drink one glass of water every hour after the test to hasten the excretion of the radioisotope.
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Preparation for the test
You are to fast for a minimum of 6 hours prior to the test (no food or drink, including water). No smoking for a minimum of 2 hours before the test. The medications listed below should NOT be taken prior to the test. Consult your doctor before stopping any medications.
Exclusion Period Type of Medication Generic Name Trade Names Four Weeks Antibiotics Amoxycillin (Penicillins) Abbocillin, Alphamox, Amoxil, Augmentin, Bgramin, Cilamox, Clamoxyl, Clavulin, Clavycillin, Curam, Fisamox, Maxamox, Moxiclav, Ranmoxy, Yomax Ampicillin (Penicillins) Ampicyn, Austrapen, Ibimicyn Azithromycin (Macrolides) Azith, Zedd, Zithromax, Zitrocin Cefaclor (Cephalosporins) Ceclor, Karlor, Keflor, Ozcef Cephalexin Cephatrust, Cilex, Keflex, Ialex, Ibilex, Rancef Ciprofloxacin (Quinolones) C-Flox, Cifran, Ciprol, Ciproxin, Proquin Clarithromycin (Macrolides) Clarac, Clarihexal, Clarithro, Kalixocin, Klacid Erythromycin (Macrolides) EES, E-Mycin, Eryc, Erythrocin Metronidazole Flagyl, Metronide, Metrogyl, Simplotan Rifaximin Xifaxan Roxithromycin (Macrolides) Biaxsig, Roxar, Roximycin, Rulide Tetracyclines Akamin, Doryx, Doxsig, Doxy, Doxycycline, Doxyhexal, Doxylin, Frakas, Minocycline, Minomycin, Tetracycline, Vibra-tabs Trindaxole Fasigyn 30 Days Prior to Test Other Anti-infectives Bismuth Denol, Helldac 14 Days Prior to Test Cytoprotectives Sucralfate Carafate, Ulcyte 7 Days Prior to Test Proton Pump Inhibitors Lansoprazole Lanzopran, Zopral, Zoton Rabeprazole Parzol, Pariet, Prabez, Rabzole, Razit Omeprazole Acimax, Losec, Meprazol, Maxor, Omepral, Omepro-GA, Pemzo, Ozmep, Probitor Esomeprazole Nexium Pantoprazole Gastenz, Ozpan, Panthron, Panto, Pantofast, Pantoloc, Pantomac, Pantozol, Salpraz, Somac, Sozol, Suvacid, Torzole During Fasting and During Test Antacids ALU-TAB, Andrews Tums Antacid, DeWitts Antacid Powder, ENO, Gastrogel, Gaviscon, Mylanta, Rennie, Titralac During Fasting and During Test H2 Antagonists Cimetidine Magicul, Tagamet Ranitidine Ausran, Rani 2, Ranital, Ranoxyl, Ulcaid, Ultac,
ZantacFamotidine Ausfam, Famohexal, Pamacid, Pepcidine, Pepzan Nizatidine Nizac, Tacidine, Tazac The above is not an exhaustive list. If you are unsure about the classification of a medication, please consult your doctor or pharmacist.
Please note: While it is preferable that you have FULLY complied with the testing requirements, testing can be conducted if, for example, certain medications cannot be stopped as advised by your doctor. In these cases, ensure this is clearly documented in the questionnaire you will complete before your test.
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Collection procedure
- You will be required to swallow a capsule (do not chew) with approximately 30mL of
water.
Do not handle the capsule directly.
(PYtest® Capsule AST R 67146 containing 37 kBq 14C-urea) - Three minutes later, you will be required to swallow a further 30mL of water.
- You will then wait for 7 minutes and be instructed to take a deep breath, hold for approximately 10 seconds, and blow into a balloon until it is firm.
- You will be required to swallow a capsule (do not chew) with approximately 30mL of
water.
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Answers to commonly asked questions
- It is OK to have brushed your teeth before testing.
- It is OK to have used an asthma puffer.
- It is OK to have had a sip (5-10 mL) of water in the last 6 hours, but no more than that.
- Taking vitamins or herbal supplements in the last 4 weeks will NOT interfere with the test.
Important: Testing for cure or eradication of H. pylori should only be performed at least 4 weeks after completion of antibiotic therapy, not sooner.
Related Pages
Helicobacter Pylori Testing
Helicobacter pylori is a common stomach infection in Australia that can cause ulcers and increase the risk of stomach cancer; testing and treatment help prevent serious complications.
Patient Test Instructions
Prepare for your pathology test with Clinical Labs by following specific instructions to ensure accurate results and the best possible collection experience.
FAQ
Find answers to common pathology test questions, including preparation, fasting guidelines, collection centre locations, opening hours and aftercare tips at Clinical Labs.