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Osteoporosis affects over 75 million men and women worldwide and places 1 out of every 2 women at the risk of developing bone fractures.  Unfortunately the degenerative disease is often not detected until it is well advanced and a bone fracture (most commonly the hip) is usually one of the first symptoms.  Early detection of osteoporosis can help to facilitate successful treatment and reduce the risk of further advancement of the disease.

The Osteoporosis Risk Assessment (NTx) is a urine test which measures the risk of osteoporosis by detecting the rate of bone resorption (breakdown) well before significant changes are obvious on bone mineral density scans.  Research indicates that elevated bone resorption is the primary cause of age-related bone loss and low bone mass is the major cause of osteoporosis.

Once osteoporosis has been diagnosed, quantitative measures of the excretion of cross-linked N-telopeptide (NTx), type 1 bone collagen, provide an indicator of human bone resportion.

The NTx marker can also be used to monitor the efficacy of anti-resportive therapies such as hormone replacement (HRT) and/or calcium supplementation in postmenopausal women, individuals with osteoporosis and those with Paget's disease.


Test Kit

Once the practitioner has given the patient their request form the patient can order their test kit online at Clinicallabs.com.au or by calling Australian Clinical Labs Functional Pathology customer service on 1300 55 44 80 between the hours of 9:00am and 5:00pm AEST. The test kit contains full instructions.


Specimen Requirements

One urine specimen collected from the second morning void (the second urine after waking in the morning).  The test kit provided contains everything required to complete the test.


Turnaround Time

The standard turnaround time for this test is 10 – 14 working days from the date the patient’s specimen/s are received by our laboratory.


Test Results

Patient results are delivered via electronic download unless requested otherwise. Results can also be issued via hardcopy, fax or web based e-viewer.


Technical Support

All Australian Clinical Labs Functional Pathology tests are accompanied by an Interpretive Guide to assist practitioners in their clinical understanding and patient management for each result. Australian Clinical Labs Functional Pathology also has experienced full time Technical Advisors available for practitioners to discuss appropriate test selection, interpretation of test results, individual cases and other technical matters. Please call 1300 55 44 80 between the hours of 9:00am and 5:00pm  AEST or email csfp@AustralianClinicalLabs.com.au