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Helicobacter Pylori C14 Urea Breath Test

Helicobacter Pylori - Urea Breath Test C14


Purpose of this test

This test is used for detecting the presence of bacteria called Helicobacter which can cause stomach inflammation. It may also be used to check that the bacteria has been eradicated after treatment. 

Note for referrers: Please consult with the Clinical Labs chemical pathologist in your state before proceeding if the patient is pregnant, breast feeding or think they may be pregnant, or if the patient is a child under 16 years old.

Day before test

You are to fast for a minimum 4-6 hours prior to the test. However, any prescription medication other than those listed below can be taken with a sip of water.

The following medications should NOT be taken prior to the test.

Exclusion Period Type of Medication Generic Name Trade Names

Four Weeks

Antibiotics

All Antibiotics except Vancomycin
and Sulphonamides
Bactrim, Septrin, etc.
Four Weeks Ingredient in antacids, antidiarrheal & GI medication Bismuth Denol, Helldac
14 Days  Cytoprotectives Sucralfate Carafate, Ulcyte, SCF
7 Days Proton Pump Inhibitors Lanozaprole, Rabeprazole,
Esomeprazole, Pantoprazole
Zoton, Pariet, Losec, Losec IV, Maxor, Nexium, Somac
During fasting and
during Test
Antacids ALU-tab, Andrews TUMS, Antassa, De Wits antacid powder, Daxal, ENO, Gastrogel,
Gaviscon, Gelusil, Medefoam2, Meracote, Mucaine, Mylanta, Rennie, Salvital,
Sigma Liquid antacid, Titralec
During fasting and
during Test
H2 Antagonists Cimetidine, Ranitidine,
Famotidine, 
Nizatidine
Cinetimax, Cimehaxal, SBPA- Ranitidine, Magicul, Sigmetadine, Tagamet, WL-
Cimetidine, Ranitdine BC Genrx Ranitdine, Rani 2, Hexal Ranitic, SBPA-
Ranitidine, Ranihexal, Zantac, Ausran, Ranoxyl Amfamox, Pepcid, Pepcidine Tazac

Collection Procedure


1. You will be required to swallow a capsule with approximately 30mls of water. PYtest® Capsule AST R 67146 containing 37 kBq 14C-Urea. 

2. Three minutes later you will be required to swallow a further 30mls of water.

3. You will then wait for 7 minutes, and then be instructed to take a deep breath, hold for approximately 10 seconds, and blow into a balloon until it is firm.

Note: Confirmatory tests post antibiotic treatment for Helicobacter Pylori cannot be done until a minimum of 6-8 weeks following completion of the course.

Download patient instructions